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Anti-Human ZC3H12D Polyclonal Antibody (HP358014)

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概述
货号HP358014
品牌abinScience
种属反应性Human, Mouse
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human ZC3H12D (Arg90-Pro231).
靶标Probable ribonuclease ZC3H12D, MCP-induced protein 4, Zinc finger CCCH domain-containing protein 12D, TFL, Transformed follicular lymphoma, p34, MCPIP4, ZC3H12D, C6orf95
纯化方式Purified by antigen affinity column.
Accession号A2A288
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Probable ribonuclease ZC3H12D is a ~58 kDa protein. May regulate cell growth likely by suppressing RB1 phosphorylation. May function as RNase and regulate the levels of target RNA species (Potential). In association with ZC3H12A enhances the degradation of interleukin IL-6 mRNA level in activated macrophages. Serve as a tumor suppressor in certain leukemia cells. Overexpression inhibits the G1 to S phase progression through suppression of RB1 phosphorylation.

1. Minagawa, K. et al. (2009) Molecular cancer research : MCR 7, 880-9. PMID: 19531561
2. Huang, S. et al. (2015) The Journal of biological chemistry 290, 20782-20792. PMID: 26134560
3. Wang, M. et al. (2007) Cancer research 67, 93-9. PMID: 17210687
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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