Anti-Mouse VLDLR Polyclonal Antibody (MX210014)

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50ug
100ug

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MX210014

abinScience

种属反应性

Human, Mouse, Rat

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Mouse VLDLR (Glu440-Asn684).

Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R)

Purified by antigen affinity column.

Accession号

P98156

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Very low-density lipoprotein receptor (VLDLR) is a ~96 kDa protein. Multifunctional cell surface receptor that binds VLDL and transports it into cells by endocytosis and therefore plays an important role in energy metabolism. Also binds to a wide range of other molecules including Reelin/RELN or apolipoprotein E/APOE-containing ligands as well as clusterin/CLU. In the off-state of the pathway LRP8 and VLDLR form homo or heterooligomers. Upon binding to ligands, homooligomers are rearranged to higher order receptor clusters that transmit the extracellular RELN signal to intracellular signaling processes by binding to DAB1 on its cytoplasmic tail. This interaction results in phosphorylation of DAB1 leading to the ultimate cell responses required for the correct positioning of newly generated neurons.

1. Tacken, PJ. et al. (2000) Journal of lipid research 41, 2055-62. PMID: 11108739

2. Nguyen, A. et al. (2014) The Journal of biological chemistry 289, 1688-703. PMID: 24293365

3. Fuchigami, T. et al. (2013) Genes to cells : devoted to molecular & cellular mechanisms 18, 410-24. PMID: 23506116

4. Hack, I. et al. (2007) Development (Cambridge, England) 134, 3883-91. PMID: 17913789

For research use only.

产品说明书

Anti-Mouse VLDLR Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

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实验相关试剂

Anti-Mouse VLDLR Polyclonal Antibody (MX210014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse VLDLR Polyclonal Antibody (MX210014)

概述

图片

参考文献

产品说明书

相关产品推荐

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