Anti-Mouse CD69 Polyclonal Antibody (MC273014)

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50ug
100ug

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MC273014

abinScience

种属反应性

Mouse

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Mouse CD69 (His81-Arg199).

Early activation antigen CD69 (CD antigen CD69)

内毒素水平

Please contact with the lab for this information.

Purified by antigen affinity column.

Accession号

P37217

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Early activation antigen CD69 is a ~22 kDa protein. Transmembrane protein expressed mainly on T-cells resident in mucosa that plays an essential role in immune cell homeostasis. Rapidly expressed on the surface of platelets, T-lymphocytes and NK cells upon activation by various stimuli, such as antigen recognition or cytokine signaling, stimulates different signaling pathways in different cell types. Negatively regulates Th17 cell differentiation through its carbohydrate dependent interaction with galectin-1/LGALS1 present on immature dendritic cells. Association of CD69 cytoplasmic tail with the JAK3/STAT5 signaling pathway regulates the transcription of RORgamma/RORC and, consequently, differentiation toward the Th17 lineage. Also acts via the S100A8/S100A9 complex present on peripheral blood mononuclear cells to promote the conversion of naive CD4 T-cells into regulatory T-cells.

1. Martín, P. et al. (2010) Molecular and cellular biology 30, 4877-89. PMID: 20696842

2. Bui, DV. et al. (2024) Biomolecules 14. PMID: 38540778

3. Shiow, LR. et al. (2006) Nature 440, 540-4. PMID: 16525420

For research use only.

产品说明书

Anti-Mouse CD69 Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse CD69 Polyclonal Antibody (MC273014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse CD69 Polyclonal Antibody (MC273014)

概述

图片

参考文献

产品说明书

相关产品推荐

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