Anti-Mouse LRRC32/GARP Polyclonal Antibody (MC573014)

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50ug
100ug

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概述
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参考文献
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MC573014

abinScience

种属反应性

Mouse

ELISA, IHC, WB

Rabbit

Polyclonal

E. coli - derived recombinant Mouse LRRC32/GARP (Cys27-Asn276).

Transforming growth factor beta activator LRRC32 (Garpin) (Glycoprotein A repetitions predominant) (GARP) (Leucine-rich repeat-containing protein 32)

Purified by antigen affinity column.

Accession号

G3XA59

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Transforming growth factor beta activator LRRC32 (GARP) is a ~72 kDa protein. Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta. Able to outcompete LTBP1 for binding to LAP regulatory chain of TGF-beta. Controls activation of TGF-beta-1 (TGFB1) on the surface of activated regulatory T-cells (Tregs). Required for epithelial fusion during palate development by regulating activation of TGF-beta-3 (TGFB3).

1. Edwards, JP. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 193, 2843-9. PMID: 25127859

2. Wu, BX. et al. (2017) The Journal of biological chemistry 292, 18091-18097. PMID: 28912269

For research use only.

产品说明书

Anti-Mouse LRRC32/GARP Polyclonal Antibody.pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse LRRC32/GARP Polyclonal Antibody (MC573014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse LRRC32/GARP Polyclonal Antibody (MC573014)

概述

图片

参考文献

产品说明书

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