

| 货号 | MV678014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 种属反应性 | Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse IL31 (Ala31-Cys163). | ||||||||
| 经测试应用 | WB | ||||||||
| 靶标 | Interleukin-31 (IL-31) | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q6EAL8 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Interleukin-31 (IL31) is a ~18 kDa protein. Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. May function in skin immunity. Enhances myeloid progenitor cell survival in vitro. Induces RETNLA and serum amyloid A protein expression in macrophages. 1. Dillon, SR. et al. (2004) Nature immunology 5, 752-60. PMID: 15184896 2. Broxmeyer, HE. et al. (2007) Experimental hematology 35, 78-86. PMID: 17379091 3. Edukulla, R. et al. (2015) The Journal of biological chemistry 290, 13510-20. PMID: 25847241 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-IL31 polyclonal antibody at 1µg/ml on various samples.
Lane 1: RAW264.7 cell lysate
Lane 2: Mouse lung lysate



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