

| 货号 | MV592014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 种属反应性 | Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse CD321/F11R (Gly53-Glu233). | ||||||||
| 靶标 | Junctional adhesion molecule A (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (CD antigen CD321) | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | O88792 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Junctional adhesion molecule A (CD321/F11R) is a ~32 kDa protein. Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration. 1. Ebnet, K. et al. (2001) The EMBO journal 20, 3738-48. PMID: 11447115 2. Martìn-Padura, I. et al. (1998) The Journal of cell biology 142, 117-27. PMID: 9660867 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-F11R polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse lung lysate
Lane 2: Rat lung lysate



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