

| 货号 | HA291014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human VPS8 Polyclonal Antibody (HA291014) is a rabbit polyclonal antibody detecting VPS8 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human VPS8 (Val819-Glu966). | ||||||||
| 靶标 | VPS8, KIAA0804, Vacuolar protein sorting-associated protein 8 homolog | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q8N3P4 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Vacuolar protein sorting-associated protein 8 homolog (VPS8) is a ~161 kDa protein. Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations. Functions predominantly in APPL1-containing endosomes. 1. Perini, ED. et al. (2014) Traffic (Copenhagen, Denmark) 15, 1366-89. PMID: 25266290 | ||||||||
| Note | For research use only. |

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