Anti-PQBP1 Polyclonal Antibody (HF653014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HF653014

品牌

abinScience

描述

Anti-PQBP1 Polyclonal Antibody (HF653014) is a rabbit polyclonal antibody detecting PQBP1 in ELISA, IHC, WB. Suitable for Bovine, Human, Mouse, Pongo pygmaeus, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human PQBP1 (Met1-Asp265).

靶标

NPW38, PQBP1, Polyglutamine tract-binding protein 1, PQBP-1, Npw38, 38 kDa nuclear protein containing a WW domain, Polyglutamine-binding protein 1

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

O60828

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Polyglutamine-binding protein 1 (PQBP1) is a ~30 kDa protein. Intrinsically disordered protein that acts as a scaffold, and which is involved in different processes, such as pre-mRNA splicing, transcription regulation, innate immunity and neuron development. Interacts with splicing-related factors via the intrinsically disordered region and regulates alternative splicing of target pre-mRNA species. May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-induced cell death.

1. Komuro, A. et al. (1999) Nucleic acids research 27, 1957-65. PMID: 10198427

2. Waragai, M. et al. (1999) Human molecular genetics 8, 977-87. PMID: 10332029

3. Okazawa, H. et al. (2002) Neuron 34, 701-13. PMID: 12062018

4. Tapia, VE. et al. (2010) The Journal of biological chemistry 285, 19391-401. PMID: 20410308

5. Wang, Q. et al. (2013) Genes & development 27, 615-26. PMID: 23512658

Note

For research use only.

图片

参考文献

产品说明书

Anti-PQBP1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-PQBP1 Polyclonal Antibody (HF653014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-PQBP1 Polyclonal Antibody (HF653014)

概述

图片

参考文献

产品说明书

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