

| 货号 | HA110014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human UBASH3B Polyclonal Antibody (HA110014) is a rabbit polyclonal antibody detecting UBASH3B in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human UBASH3B (Gln382-Asp626). | ||||||||
| 靶标 | Tyrosine-protein phosphatase STS1/TULA2, TULA-2, STS1, Suppressor of T-cell receptor signaling 1, Ubiquitin-associated and SH3 domain-containing protein B, Cbl-interacting protein p70, STS-1, T-cell ubiquitin ligand 2, KIAA1959, UBASH3B | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q8TF42 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Ubiquitin-associated and SH3 domain-containing protein B (UBASH3B) is a ~72 kDa protein. Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination. | ||||||||
| Note | For research use only. |

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