Anti-Human ATP13A1 Polyclonal Antibody (HA160014)

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50ug
100ug

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概述
图片
参考文献
产品说明书

概述

货号

HA160014

品牌

abinScience

描述

Anti-Human ATP13A1 Polyclonal Antibody (HA160014) is a rabbit polyclonal antibody detecting ATP13A1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human ATP13A1 (Ser542-Ser722).

靶标

Endoplasmic reticulum P5A-ATPase, KIAA1825, ATP13A1, Endoplasmic reticulum transmembrane helix translocase, ATP13A

纯化方式

Purified by antigen affinity column.

Accession号

Q9HD20

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Endoplasmic reticulum transmembrane helix translocase (ATP13A1) is a ~132 kDa protein. Endoplasmic reticulum translocase required to remove mitochondrial transmembrane proteins mistargeted to the endoplasmic reticulum. Acts as a dislocase that mediates the ATP-dependent extraction of mislocalized mitochondrial transmembrane proteins from the endoplasmic reticulum membrane. Specifically binds mitochondrial tail-anchored transmembrane proteins: has an atypically large substrate-binding pocket that recognizes and binds moderately hydrophobic transmembranes with short hydrophilic lumenal domains.

1. McKenna, MJ. et al. (2020) Science (New York, N.Y.) 369. PMID: 32973005

2. Guna, A. et al. (2022) Science (New York, N.Y.) 378, 317-322. PMID: 36264797

Note

For research use only.

图片

Western blot

Western blot analysis was performed using anti-ATP13A1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse heart lysate
Lane 2: Mouse brain lysate

参考文献

产品说明书

Anti-Human ATP13A1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ATP13A1 Polyclonal Antibody (HA160014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ATP13A1 Polyclonal Antibody (HA160014)

概述

图片

参考文献

产品说明书

相关产品推荐

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