Anti-Human PNPLA3 Polyclonal Antibody (HA111014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HA111014

品牌

abinScience

描述

Anti-Human PNPLA3 Polyclonal Antibody (HA111014) is a rabbit polyclonal antibody detecting PNPLA3 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human PNPLA3 (Met1-Lys252).

靶标

1-acylglycerol-3-phosphate O-acyltransferase PNPLA3, iPLA2-epsilon, C22orf20, Lysophosphatidic acid acyltransferase, Acylglycerol transacylase, Calcium-independent phospholipase A2-epsilon, Patatin-like phospholipase domain-containing protein 3, ADPN, Adiponutrin, PNPLA3

纯化方式

Purified by antigen affinity column.

Accession号

Q9NST1

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 is a ~52 kDa protein. Specifically catalyzes coenzyme A (CoA)-dependent acylation of 1-acyl-sn-glycerol 3-phosphate (2-lysophosphatidic acid/LPA) to generate phosphatidic acid (PA), an important metabolic intermediate and precursor for both triglycerides and glycerophospholipids. Does not esterify other lysophospholipids. Acyl donors are long chain (at least C16) fatty acyl-CoAs: arachidonoyl-CoA, linoleoyl-CoA, oleoyl-CoA and at a lesser extent palmitoyl-CoA. Additionally possesses low triacylglycerol lipase and CoA-independent acylglycerol transacylase activities and thus may play a role in acyl-chain remodeling of triglycerides. In vitro may express hydrolytic activity against glycerolipids triacylglycerol, diacylglycerol and monoacylglycerol, with a strong preference for oleic acid as the acyl moiety.

1. Kumari, M. et al. (2012) Cell metabolism 15, 691-702. PMID: 22560221

2. Jenkins, CM. et al. (2004) The Journal of biological chemistry 279, 48968-75. PMID: 15364929

3. He, S. et al. (2010) The Journal of biological chemistry 285, 6706-15. PMID: 20034933

4. Huang, Y. et al. (2011) The Journal of biological chemistry 286, 37085-93. PMID: 21878620

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human PNPLA3 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human PNPLA3 Polyclonal Antibody (HA111014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human PNPLA3 Polyclonal Antibody (HA111014)

概述

图片

参考文献

产品说明书

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