Anti-Human UVRAG Polyclonal Antibody (HA311014)

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100ug

数量：

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概述
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参考文献
产品说明书

概述

货号

HA311014

品牌

abinScience

描述

Anti-Human UVRAG Polyclonal Antibody (HA311014) is a rabbit polyclonal antibody detecting UVRAG in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human UVRAG (Arg41-Ala164).

靶标

UV radiation resistance-associated gene protein, p63, UVRAG

纯化方式

Purified by antigen affinity column.

Accession号

Q9P2Y5

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

UV radiation resistance-associated gene protein (UVRAG) is a ~78 kDa protein. Versatile protein that is involved in regulation of different cellular pathways implicated in membrane trafficking. Involved in regulation of the COPI-dependent retrograde transport from Golgi and the endoplasmic reticulum by associating with the NRZ complex; the function is dependent on its binding to phosphatidylinositol 3-phosphate (PtdIns(3)P). During autophagy acts as a regulatory subunit of the alternative PI3K complex II (PI3KC3-C2) that mediates formation of phosphatidylinositol 3-phosphate and is believed to be involved in maturation of autophagosomes and endocytosis. Activates lipid kinase activity of PIK3C3. Involved in the regulation of degradative endocytic trafficking and cytokinesis, and in regulation of ATG9A transport from the Golgi to the autophagosome; the functions seems to implicate its association with PI3KC3-C2.

1. Liang, C. et al. (2006) Nature cell biology 8, 688-99. PMID: 16799551

2. Liang, C. et al. (2008) Nature cell biology 10, 776-87. PMID: 18552835

3. Thoresen, SB. et al. (2010) Experimental cell research 316, 3368-78. PMID: 20643123

4. He, S. et al. (2013) Nature cell biology 15, 1206-1219. PMID: 24056303

5. Cheng, X. et al. (2017) Molecular cell 65, 1029-1043.e5. PMID: 28306502

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human UVRAG Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human UVRAG Polyclonal Antibody (HA311014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human UVRAG Polyclonal Antibody (HA311014)

概述

图片

参考文献

产品说明书

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