Anti-Human AKAP8L Polyclonal Antibody (HA275014)

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50ug
100ug

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概述
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参考文献
产品说明书

概述

货号

HA275014

品牌

abinScience

描述

Anti-Human AKAP8L Polyclonal Antibody (HA275014) is a rabbit polyclonal antibody detecting AKAP8L in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human AKAP8L (Thr354-Gly565).

靶标

Helicase A-binding protein 95, AKAP8L, Neighbor of AKAP95, Neighbor of A-kinase-anchoring protein 95, Homologous to AKAP95 protein, A-kinase anchor protein 8-like, AKAP8-like protein, HA95, NAKAP, NAKAP95, HAP95

纯化方式

Purified by antigen affinity column.

Accession号

Q9ULX6

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

A-kinase anchor protein 8-like (AKAP8L) is a ~71 kDa protein. Could play a role in constitutive transport element (CTE)-mediated gene expression by association with DHX9. Increases CTE-dependent nuclear unspliced mRNA export. Proposed to target PRKACA to the nucleus but does not seem to be implicated in the binding of regulatory subunit II of PKA. May be involved in nuclear envelope breakdown and chromatin condensation. May be involved in anchoring nuclear membranes to chromatin in interphase and in releasing membranes from chromating at mitosis.

1. Westberg, C. et al. (2000) The Journal of biological chemistry 275, 21396-401. PMID: 10748171

2. Yang, JP. et al. (2001) The Journal of biological chemistry 276, 30694-700. PMID: 11402034

3. Orstavik, S. et al. (2000) Biology of the cell 92, 27-37. PMID: 10761695

4. Han, I. et al. (2002) Molecular and cellular biology 22, 2136-46. PMID: 11884601

5. Martins, SB. et al. (2000) Journal of cell science 113 Pt 21, 3703-13. PMID: 11034899

6. Martins, S. et al. (2003) The Journal of cell biology 160, 177-88. PMID: 12538639

7. Li, Y. et al. (2006) Genes & development 20, 2566-79. PMID: 16980585

8. Kvissel, AK. et al. (2007) Experimental cell research 313, 2795-809. PMID: 17594903

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human AKAP8L Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human AKAP8L Polyclonal Antibody (HA275014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human AKAP8L Polyclonal Antibody (HA275014)

概述

图片

参考文献

产品说明书

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