

| 货号 | MY505014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Mouse CFH Polyclonal Antibody (MY505014) is a rabbit polyclonal antibody detecting CFH in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 种属反应性 | Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse CFH (Asn29-Glu207). | ||||||||
| 靶标 | Complement factor H, CFH, H factor 1, HF1, HF, HF2 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P06909 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Complement factor H (CFH) is a ~139 kDa protein. Glycoprotein that plays an essential role in maintaining a well-balanced immune response by modulating complement activation. Acts as a soluble inhibitor of complement, where its binding to self markers such as glycan structures prevents complement activation and amplification on cell surfaces. Accelerates the decay of the complement alternative pathway (AP) C3 convertase C3bBb, thus preventing local formation of more C3b, the central player of the complement amplification loop. As a cofactor of the serine protease factor I, CFH also regulates proteolytic degradation of already-deposited C3b. In addition, mediates several cellular responses through interaction with specific receptors. | ||||||||
| Note | For research use only. |

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