

| 货号 | MF815014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Mouse CD8A Polyclonal Antibody (MF815014) is a rabbit polyclonal antibody detecting CD8a in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 种属反应性 | Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse CD8A (Ala31-Lys148). | ||||||||
| 靶标 | CD8a, Cd8a, Lyt-2, Lyt2, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯度 | >90% as determined by SDS-PAGE. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P01731 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | T-cell surface glycoprotein CD8 alpha chain (CD8a/Lyt2) is a ~27 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. | ||||||||
| Note | For research use only. |

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