Anti-Mouse OSTN Polyclonal Antibody (MX160014)

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概述
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参考文献
产品说明书

概述

货号

MX160014

品牌

abinScience

描述

Anti-Mouse OSTN Polyclonal Antibody (MX160014) is a rabbit polyclonal antibody detecting OSTN in ELISA, IHC, WB. Suitable for Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Mouse OSTN (Phe26-Gly130).

靶标

OSTN, Osteocrin, Musclin

纯化方式

Purified by antigen affinity column.

Accession号

P61364

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Osteocrin (OSTN) is a ~14 kDa protein. Hormone that acts as a ligand for natriuretic peptide receptor NPR3/NPR-C and promotes bone growth and physical endurance in muscle. Acts as a regulator of osteoblast differentiation and bone growth by binding to natriuretic peptide receptor NPR3/NPR-C, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production. Required to enhance physical endurance: induced following physical exercise in muscle and promotes cGMP production, probably by interacting with NPR3/NPR-C. May act as an autocrine and paracrine factor linked to glucose metabolism in skeletal muscle.

1. Thomas, G. et al. (2003) The Journal of biological chemistry 278, 50563-71. PMID: 14523025

2. Moffatt, P. et al. (2007) The Journal of biological chemistry 282, 36454-62. PMID: 17951249

3. Subbotina, E. et al. (2015) Proceedings of the National Academy of Sciences of the United States of America 112, 16042-7. PMID: 26668395

4. Nishizawa, H. et al. (2004) The Journal of biological chemistry 279, 19391-5. PMID: 15044443

Note

For research use only.

图片

参考文献

产品说明书

Anti-Mouse OSTN Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse OSTN Polyclonal Antibody (MX160014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse OSTN Polyclonal Antibody (MX160014)

概述

图片

参考文献

产品说明书

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