

| 货号 | HF521014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human LDLR Polyclonal Antibody (HF521014) is a rabbit polyclonal antibody detecting LDLR in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human LDLR (Gly193-Arg788). | ||||||||
| 靶标 | LDLR, Low-density lipoprotein receptor, LDL receptor | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P01130 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Low-density lipoprotein receptor (LDLR) is a ~95 kDa protein. Binds low density lipoprotein /LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Forms a ternary complex with PGRMC1 and TMEM97 receptors which increases LDLR-mediated LDL internalization. 1. Riad, A. et al. (2018) Scientific reports 8, 16845. PMID: 30443021 | ||||||||
| Note | For research use only. |

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