Anti-Human PTPRQ Polyclonal Antibody (HA962014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HA962014

品牌

abinScience

描述

Anti-Human PTPRQ Polyclonal Antibody (HA962014) is a rabbit polyclonal antibody detecting PTPRQ in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human PTPRQ (Arg1929-Met2299).

靶标

Phosphatidylinositol phosphatase PTPRQ, R-PTP-Q, PTP-RQ, PTPRQ, Receptor-type tyrosine-protein phosphatase Q

纯化方式

Purified by antigen affinity column.

Accession号

Q9UMZ3

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Phosphatidylinositol phosphatase PTPRQ is a ~260 kDa protein. Dephosphorylates phosphatidylinositol phosphates, such as phosphatidylinositol 3,4,5-trisphosphate (PIP3) and phosphatidylinositol 3,5-diphosphates, with preference for PIP3. Phosphate can be hydrolyzed from the D3 and D5 positions in the inositol ring. Has low tyrosine-protein phosphatase activity in vitro; however, the relevance of such activity in vivo is unclear. Plays an important role in adipogenesis of mesenchymal stem cells (MSCs). Regulates the phosphorylation state of AKT1 by regulating the levels of PIP3 in MSCs and preadipocyte cells.

1. Yu, KR. et al. (2013) Acta crystallographica. Section D, Biological crystallography 69, 1522-9. PMID: 23897475

2. Jung, H. et al. (2009) Biochemical and biophysical research communications 383, 252-7. PMID: 19351528

3. Shahin, H. et al. (2010) Journal of medical genetics 47, 643-5. PMID: 20472657

4. Eisenberger, T. et al. (2018) Genetics in medicine : official journal of the American College of Medical Genetics 20, 614-621. PMID: 29309402

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human PTPRQ Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human PTPRQ Polyclonal Antibody (HA962014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human PTPRQ Polyclonal Antibody (HA962014)

概述

图片

参考文献

产品说明书

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