Anti-Human RACK1 Polyclonal Antibody (HX977014)

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概述
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参考文献
产品说明书

概述

货号

HX977014

品牌

abinScience

描述

Anti-Human RACK1 Polyclonal Antibody (HX977014) is a rabbit polyclonal antibody detecting RACK1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human RACK1 (Met1-Arg317).

靶标

RACK1, Human lung cancer oncogene 7 protein, Guanine nucleotide-binding protein subunit beta-like protein 12.3, GNB2L1, Cell proliferation-inducing gene 21 protein, Guanine nucleotide-binding protein subunit beta-2-like 1, Receptor of activated protein C kinase 1, Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed, Receptor for activated C kinase, Small ribosomal subunit protein RACK1, HLC-7

纯化方式

Purified by antigen affinity column.

Accession号

P63244

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Small ribosomal subunit protein RACK1 is a ~35 kDa protein. Scaffolding protein involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes. Component of the 40S ribosomal subunit involved in translational repression. Involved in the initiation of the ribosome quality control (RQC), a pathway that takes place when a ribosome has stalled during translation, by promoting ubiquitination of a subset of 40S ribosomal subunits. Binds to and stabilizes activated protein kinase C (PKC), increasing PKC-mediated phosphorylation.

1. Anger, AM. et al. (2013) Nature 497, 80-5. PMID: 23636399

2. Sundaramoorthy, E. et al. (2017) Molecular cell 65, 751-760.e4. PMID: 28132843

3. Ikebuchi, Y. et al. (2009) Hepatology research : the official journal of the Japan Society of Hepatology 39, 1091-107. PMID: 19674157

4. Cao, XX. et al. (2011) Breast cancer research and treatment 126, 555-63. PMID: 20499158

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human RACK1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human RACK1 Polyclonal Antibody (HX977014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human RACK1 Polyclonal Antibody (HX977014)

概述

图片

参考文献

产品说明书

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