Anti-Human RCC2 Polyclonal Antibody (HA217014)

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概述
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概述

货号

HA217014

品牌

abinScience

描述

Anti-Human RCC2 Polyclonal Antibody (HA217014) is a rabbit polyclonal antibody detecting Protein RCC2 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human RCC2 (Glu89-Arg501).

靶标

Protein RCC2, Telophase disk protein of 60 kDa, RCC2, RCC1-like protein TD-60, KIAA1470, TD60

纯化方式

Purified by antigen affinity column.

Accession号

Q9P258

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Protein RCC2 is a ~56 kDa protein. Multifunctional protein that may affect its functions by regulating the activity of small GTPases, such as RAC1 and RALA. Required for normal progress through the cell cycle, both during interphase and during mitosis. Required for the presence of normal levels of MAD2L1, AURKB and BIRC5 on inner centromeres during mitosis, and for normal attachment of kinetochores to mitotic spindles. Required for normal organization of the microtubule cytoskeleton in interphase cells. Functions as guanine nucleotide exchange factor (GEF) for RALA.

1. Mollinari, C. et al. (2003) Developmental cell 5, 295-307. PMID: 12919680

2. Williamson, RC. et al. (2014) Journal of cell science 127, 4292-307. PMID: 25074804

3. Papini, D. et al. (2015) Nature communications 6, 7678. PMID: 26158537

4. Song, C. et al. (2018) Oncogene 37, 8-17. PMID: 28869598

5. Yenjerla, M. et al. (2013) Cell cycle (Georgetown, Tex.) 12, 837-41. PMID: 23388455

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human RCC2 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human RCC2 Polyclonal Antibody (HA217014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human RCC2 Polyclonal Antibody (HA217014)

概述

图片

参考文献

产品说明书

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