Anti-Human RHOA Polyclonal Antibody (HX184014)

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概述
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参考文献
产品说明书

概述

货号

HX184014

品牌

abinScience

描述

Anti-Human RHOA Polyclonal Antibody (HX184014) is a rabbit polyclonal antibody detecting RHOA in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human RHOA (Ala2-Gly189).

靶标

Rho cDNA clone 12, ARH12, RHO12, ARHA, RHOA, Transforming protein RhoA, h12

纯化方式

Purified by antigen affinity column.

Accession号

P61586

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Transforming protein RhoA is a ~21 kDa protein. Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Mainly associated with cytoskeleton organization, in active state binds to a variety of effector proteins to regulate cellular responses such as cytoskeletal dynamics, cell migration and cell cycle. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essential role in cleavage furrow formation.

1. Wei, J. et al. (2013) Biochimica et biophysica acta 1833, 2757-2764. PMID: 23871831

2. Vabres, P. et al. (2019) Nature genetics 51, 1438-1441. PMID: 31570889

3. Quilliam, LA. et al. (1996) The Journal of biological chemistry 271, 28772-6. PMID: 8910519

4. Vincent, S. et al. (1997) Molecular and cellular biology 17, 2247-56. PMID: 9121475

5. Wing, MR. et al. (2003) The Journal of biological chemistry 278, 41253-8. PMID: 12900402

6. Kamijo, K. et al. (2006) Molecular biology of the cell 17, 43-55. PMID: 16236794

7. Wallace, SW. et al. (2011) Molecular and cellular biology 31, 81-91. PMID: 20974804

8. Dubash, AD. et al. (2013) The Journal of cell biology 202, 653-66. PMID: 23940119

9. Bristow, JM. et al. (2009) Journal of cell science 122, 4535-46. PMID: 19934221

10. Zaoui, K. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 18517-22. PMID: 20937854

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human RHOA Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human RHOA Polyclonal Antibody (HX184014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human RHOA Polyclonal Antibody (HX184014)

概述

图片

参考文献

产品说明书

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