Anti-ASFV S273R Polyclonal Antibody (VK573014)

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概述
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参考文献
产品说明书

概述

货号

VK573014

品牌

abinScience

描述

Anti-ASFV S273R Polyclonal Antibody (VK573014) is a rabbit polyclonal antibody detecting S273R in ELISA, IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

African swine fever virus (ASFV)

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant ASFV S273R (Met1-Ala273).

靶标

Cysteine protease S273R, pS273R, 3.4.22.-, Ba71V-111, S273R

纯化方式

Purified by antigen affinity column.

Accession号

Q00946

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Cysteine protease S273R is a ~31 kDa protein. Cysteine protease that plays several role during infection including processing of the structural polyprotein or inhibition of the host immune response. Catalyzes the maturation of the pp220 and pp62 polyprotein precursors into core-shell proteins. Plays a role in the disruption of host pyroptosis via specific cleavage of gasdermin D/GSDMD. In addition, strongly decreases the host cGAS-STING signaling by targeting IKBKE via its enzymatic activity. Also impairs host FOXJ1-mediated antiviral effect via degradation of FOXJ1.

1. Andrés, G. et al. (2002) Journal of virology 76, 12473-82. PMID: 12438573

2. Zhao, G. et al. (2022) The Journal of biological chemistry 298, 101480. PMID: 34890644

3. Luo, J. et al. (2022) Virulence 13, 740-756. PMID: 35437104

4. Ma, C. et al. (2022) Virologica Sinica 37, 445-454. PMID: 35513267

5. Li, T. et al. (2023) The Journal of biological chemistry 299, 104844. PMID: 37209818

6. Li, YH. et al. (2023) Journal of virology 97, e0194222. PMID: 36856422

Note

For research use only.

图片

参考文献

产品说明书

Anti-ASFV S273R Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-ASFV S273R Polyclonal Antibody (VK573014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-ASFV S273R Polyclonal Antibody (VK573014)

概述

图片

参考文献

产品说明书

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