

| 货号 | HV137014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human CD85h/LILRA2 Polyclonal Antibody (HV137014) is a rabbit polyclonal antibody detecting LILRA2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human CD85h/LILRA2 (Gly24-Val417). | ||||||||
| 靶标 | Leukocyte immunoglobulin-like receptor subfamily A member 2, CD85 antigen-like family member H, Immunoglobulin-like transcript 1, ILT-1, Leukocyte immunoglobulin-like receptor 7, LIR-7, CD85h, LILRA2, ILT1, LIR7 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q8N149 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Leukocyte immunoglobulin-like receptor subfamily A member 2 (CD85h/LILRA2) is a ~52 kDa protein. Part of the innate immune responses against microbial infection. Specifically recognizes a set of N-terminally truncated immunoglobulins that are produced via cleavage by proteases from a range of pathogenic bacteria and fungi, including L.pneumophila, M.hyorhinis, S.pneumoniae, S.aureus and C.albicans. Recognizes epitopes that are in part in the variable region of the immunoglobulin light chains, but requires also the constant region for signaling. Binds to a subset of cleaved IgM, IgG3 and IgG4 molecules, but does not bind cleaved IgA1. Binding of N-terminally truncated immunoglobulins mediates activation of neutrophils. 1. Tedla, N. et al. (2003) Proceedings of the National Academy of Sciences of the United States of America 100, 1174-9. PMID: 12529506 2. Hirayasu, K. et al. (2016) Nature microbiology 1, 16054. PMID: 27572839 3. Lu, HK. et al. (2012) PloS one 7, e33478. PMID: 22479404 4. Chen, Y. et al. (2009) Journal of molecular biology 386, 841-53. PMID: 19230061 | ||||||||
| Note | For research use only. |

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