Anti-Human PPP6C Polyclonal Antibody (HT366014)

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100ug

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概述
图片
参考文献
产品说明书

概述

货号

HT366014

品牌

abinScience

描述

Anti-Human PPP6C Polyclonal Antibody (HT366014) is a rabbit polyclonal antibody detecting PPP6C in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human PPP6C (Met1-Leu305).

靶标

Serine/threonine-protein phosphatase 6 catalytic subunit, PP6C, 3.1.3.16, Serine/threonine-protein phosphatase 6 catalytic subunit, N-terminally processed, PPP6C, PPP6

纯化方式

Purified by antigen affinity column.

Accession号

O00743

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Serine/threonine-protein phosphatase 6 catalytic subunit (PPP6C) is a ~35 kDa protein. Catalytic subunit of protein phosphatase 6 (PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. N-terminal domain restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. During mitosis, regulates spindle positioning. Down-regulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7.

1. Kajino, T. et al. (2006) The Journal of biological chemistry 281, 39891-6. PMID: 17079228

2. Tan, P. et al. (2017) Molecular cell 68, 293-307.e5. PMID: 29053956

3. Li, M. et al. (2020) Protein & cell 11, 584-599. PMID: 32474700

4. Filali, M. et al. (1999) Journal of cellular biochemistry 73, 153-63. PMID: 10227379

5. Stefansson, B. et al. (2007) Cell cycle (Georgetown, Tex.) 6, 1386-92. PMID: 17568194

6. Kotak, S. et al. (2016) Journal of cell science 129, 3015-25. PMID: 27335426

7. Ni, G. et al. (2020) mBio 11. PMID: 32753499

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human PPP6C Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human PPP6C Polyclonal Antibody (HT366014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human PPP6C Polyclonal Antibody (HT366014)

概述

图片

参考文献

产品说明书

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