

| 货号 | HT308014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human AQP7 Polyclonal Antibody (HT308014) is a rabbit polyclonal antibody detecting AQP7 in ELISA, IHC, WB. Suitable for Human.
Highlights
| ||||||||
| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human AQP7 (Phe236-Phe342). | ||||||||
| 靶标 | Aquaporin-7, AQP-7, Aquaglyceroporin-7, Aquaporin adipose, AQPap, Aquaporin-7-like, AQP7, AQP7L, AQP9 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | O14520 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
||||||||
| 产品使用信息 |
| ||||||||
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Aquaporin-7 (AQP7) is a ~37 kDa protein. Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient. Could also be permeable to urea. Mediates the efflux of glycerol, formed upon triglyceride hydrolysis, to avoid its accumulation in adipocytes and to make it available to other tissues. In the kidney, mediates the reabsorption of glycerol, preventing its loss in urine, again participating to energy homeostasis. In pancreatic beta cells, it also mediates the efflux of glycerol, regulating its intracellular levels. 1. Kondo, H. et al. (2002) European journal of biochemistry 269, 1814-26. PMID: 11952783 2. Gotfryd, K. et al. (2018) Nature communications 9, 4749. PMID: 30420639 3. Mósca, AF. et al. (2018) Cells 7. PMID: 30423801 4. Huang, P. et al. (2023) Nature communications 14, 600. PMID: 36737436 5. Kuriyama, H. et al. (1997) Biochemical and biophysical research communications 241, 53-8. PMID: 9405233 | ||||||||
| Note | For research use only. |

24小时产品查询

扫一扫关注我们

专属渠道经理