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Anti-Human SLC27A2 Polyclonal Antibody (HT300014)

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概述
货号HT300014
品牌abinScience
描述
Anti-Human SLC27A2 Polyclonal Antibody (HT300014) is a rabbit polyclonal antibody detecting SLC27A2 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human SLC27A2 (Gly283-Leu620).
靶标Long-chain fatty acid transport protein 2, Arachidonate--CoA ligase, 6.2.1.15, Fatty acid transport protein 2, FATP-2, Fatty-acid-coenzyme A ligase, very long-chain 1, Long-chain-fatty-acid--CoA ligase, 6.2.1.3, Phytanate--CoA ligase, 6.2.1.24, Solute carrier family 27 member 2, THCA-CoA ligase, 6.2.1.7, Very long-chain acyl-CoA synthetase, VLACS, VLCS, 6.2.1.-, Very long-chain-fatty-acid-CoA ligase, SLC27A2, ACSVL1, FACVL1, FATP2, VLACS
纯化方式Purified by antigen affinity column.
Accession号O14975
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Long-chain fatty acid transport protein 2 (SLC27A2) is a ~70 kDa protein. Mediates the import of long-chain fatty acids (LCFA) into the cell by facilitating their transport across cell membranes, playing an important role in hepatic fatty acid uptake. Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates, which prevents fatty acid efflux from cells and might drive more fatty acid uptake. Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. Can also activate branched-chain fatty acids such as phytanic acid and pristanic acid. May contribute to the synthesis of sphingosine-1-phosphate.

1. Steinberg, SJ. et al. (1999) Biochemical and biophysical research communications 257, 615-21. PMID: 10198260
2. Steinberg, SJ. et al. (2000) The Journal of biological chemistry 275, 15605-8. PMID: 10749848
3. Mihalik, SJ. et al. (2002) The Journal of biological chemistry 277, 24771-9. PMID: 11980911
4. Falcon, A. et al. (2010) American journal of physiology. Endocrinology and metabolism 299, E384-93. PMID: 20530735
5. Krammer, J. et al. (2011) International journal of medical sciences 8, 599-614. PMID: 22022213
6. Ohkuni, A. et al. (2013) Biochemical and biophysical research communications 442, 195-201. PMID: 24269233
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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