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Anti-Human RGS10 Polyclonal Antibody (HT099014)

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概述
货号HT099014
品牌abinScience
描述
Anti-Human RGS10 Polyclonal Antibody (HT099014) is a rabbit polyclonal antibody detecting RGS10 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human RGS10 (Ser31-Thr181).
靶标Regulator of G-protein signaling 10, RGS10, RGS10
纯化方式Purified by antigen affinity column.
Accession号O43665
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Regulator of G-protein signaling 10 (RGS10) is a ~21 kDa protein. Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the muscarinic acetylcholine receptor CHRM2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Modulates the activity of potassium channels that are activated in response to CHRM2 signaling. Activity on GNAZ is inhibited by palmitoylation of the G-protein.

1. Tu, Y. et al. (1999) The Journal of biological chemistry 274, 38260-7. PMID: 10608901
2. Burgon, PG. et al. (2001) The Journal of biological chemistry 276, 32828-34. PMID: 11443111
3. Soundararajan, M. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 6457-62. PMID: 18434541
4. Hunt, TW. et al. (1996) Nature 383, 175-7. PMID: 8774883
5. Tu, Y. et al. (1997) Science (New York, N.Y.) 278, 1132-5. PMID: 9353196
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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