Anti-Human TSPAN1 Polyclonal Antibody (HT497014)

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概述
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参考文献
产品说明书

概述

货号

HT497014

品牌

abinScience

描述

Anti-Human TSPAN1 Polyclonal Antibody (HT497014) is a rabbit polyclonal antibody detecting TSPAN1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human TSPAN1 (Tyr110-Asn211).

靶标

Tetraspanin-1, Tspan-1, Tetraspan NET-1, Tetraspanin TM4-C, TSPAN1

纯化方式

Purified by antigen affinity column.

Accession号

O60635

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Tetraspanin-1 (TSPAN1) is a ~26 kDa protein. Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Participates thereby in diverse biological functions such as cell signal transduction, adhesion, migration and protein trafficking. Regulates neuronal differentiation in response to NGF by facilitating NGF-mediated activation of NTRK1/TRKA receptor tyrosine kinase and subsequent downstream signaling pathways. Plays a role in the inhibition of TNFalpha-induced apoptosis. Mechanistically, inhibits the NF-kappa-B signaling pathway by blocking phosphorylation of CHUK.

1. Tian, J. et al. (2018) Molecular medicine reports 18, 3280-3288. PMID: 30066932

2. Yang, L. et al. (2018) Inflammation research : official journal of the European Histamine Research Society ... [et al.] 67, 951-964. PMID: 30291375

3. Nabokina, SM. et al. (2011) American journal of physiology. Gastrointestinal and liver physiology 301, G808-13. PMID: 21836059

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human TSPAN1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TSPAN1 Polyclonal Antibody (HT497014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TSPAN1 Polyclonal Antibody (HT497014)

概述

图片

参考文献

产品说明书

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