

| 货号 | HF873014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human RAMP1 Polyclonal Antibody (HF873014) is a rabbit polyclonal antibody detecting RAMP1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human RAMP1 (Cys27-Leu119). | ||||||||
| 靶标 | Receptor activity-modifying protein 1, Calcitonin-receptor-like receptor activity-modifying protein 1, CRLR activity-modifying protein 1, RAMP1 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | O60894 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Receptor activity-modifying protein 1 (RAMP1) is a ~16 kDa protein. Accessory protein that interacts with and modulates the function of G-protein coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL) and calcitonin receptor (CALCR). Required for the transport of CALCRL to the plasma membrane. Together with CALCRL, form the receptor complex for the calcitonin gene-related peptides CGRP1/CALCA and CGRP2/CALCB. Together with CALCR, form the AMYR1 receptor complex for amylin/IAPP and CGRP1/CALCA. 1. Josephs, TM. et al. (2021) Science (New York, N.Y.) 372. PMID: 33602864 2. McLatchie, LM. et al. (1998) Nature 393, 333-9. PMID: 9620797 3. Cao, J. et al. (2022) Science (New York, N.Y.) 375, eabm9609. PMID: 35324283 4. Cao, J. et al. (2024) Biochemistry 63, 1089-1096. PMID: 38603770 | ||||||||
| Note | For research use only. |

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