

| 货号 | HF932014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human E2F6 Polyclonal Antibody (HF932014) is a rabbit polyclonal antibody detecting E2F6 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human E2F6 (Pro62-Glu237). | ||||||||
| 靶标 | Transcription factor E2F6, E2F-6, E2F6 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | O75461 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Transcription factor E2F6 is a ~31 kDa protein. Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F recognition site. E2F6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. 1. Trimarchi, JM. et al. (1998) Proceedings of the National Academy of Sciences of the United States of America 95, 2850-5. PMID: 9501179 2. Gaubatz, S. et al. (1998) Proceedings of the National Academy of Sciences of the United States of America 95, 9190-5. PMID: 9689056 3. Cartwright, P. et al. (1998) Oncogene 17, 611-23. PMID: 9704927 | ||||||||
| Note | For research use only. |

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