Anti-Human SLC25A12 Polyclonal Antibody (HF639014)

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概述
图片
参考文献
产品说明书

概述

货号

HF639014

品牌

abinScience

描述

Anti-Human SLC25A12 Polyclonal Antibody (HF639014) is a rabbit polyclonal antibody detecting SLC25A12 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human SLC25A12 (Gly11-Gln311).

靶标

Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial, Araceli hiperlarga, Aralar, Aralar1, Mitochondrial aspartate glutamate carrier 1, Solute carrier family 25 member 12, SLC25A12, AGC1, ARALAR1

纯化方式

Purified by antigen affinity column.

Accession号

O75746

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial is a ~74 kDa protein. Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle. Also mediates the uptake of L-cysteinesulfinate (3-sulfino-L-alanine) by mitochondria in exchange of L-glutamate and proton. Can also exchange L-cysteinesulfinate with aspartate in their anionic form without any proton translocation. Lacks transport activity towards L-glutamine or gamma-aminobutyric acid (GABA).

1. Palmieri, L. et al. (2001) The EMBO journal 20, 5060-9. PMID: 11566871

2. Wibom, R. et al. (2009) The New England journal of medicine 361, 489-95. PMID: 19641205

3. Falk, MJ. et al. (2014) JIMD reports 14, 77-85. PMID: 24515575

4. Porcelli, V. et al. (2024) Biochimica et biophysica acta. Bioenergetics 1865, 149487. PMID: 38945283

Note

For research use only.

图片

Western blot

Western blot analysis was performed using anti-SLC25A12 polyclonal antibody at SLC25A12 on various samples.
Lane 1: Jurkat cell lysate
Lane 2: A431 cell lysate
Lane 3: Mouse brain lysate
Lane 4: Mouse skeletal muscle lysate
Lane 5: Rat brain lysate
Lane 6: Rat skeletal muscle lysate

参考文献

产品说明书

Anti-Human SLC25A12 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SLC25A12 Polyclonal Antibody (HF639014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SLC25A12 Polyclonal Antibody (HF639014)

概述

图片

参考文献

产品说明书

相关产品推荐

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