Anti-Human SASH1 Polyclonal Antibody (HF745014)

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概述
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参考文献
产品说明书

概述

货号

HF745014

品牌

abinScience

描述

Anti-Human SASH1 Polyclonal Antibody (HF745014) is a rabbit polyclonal antibody detecting SASH1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human SASH1 (Val1091-Met1247).

靶标

SAM and SH3 domain-containing protein 1, Proline-glutamate repeat-containing protein, SASH1, KIAA0790, PEPE1

纯化方式

Purified by antigen affinity column.

Accession号

O94885

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

SAM and SH3 domain-containing protein 1 (SASH1) is a ~136 kDa protein. Is a positive regulator of NF-kappa-B signaling downstream of TLR4 activation. It acts as a scaffold molecule to assemble a molecular complex that includes TRAF6, MAP3K7, CHUK and IKBKB, thereby facilitating NF-kappa-B signaling activation. Regulates TRAF6 and MAP3K7 ubiquitination. Involved in the regulation of cell mobility. Regulates lipolysaccharide (LPS)-induced endothelial cell migration.

1. Dauphinee, SM. et al. (2013) Journal of immunology (Baltimore, Md. : 1950) 191, 892-901. PMID: 23776175

2. Zhou, D. et al. (2013) Cellular signalling 25, 1526-38. PMID: 23333244

3. Courcet, JB. et al. (2015) European journal of human genetics : EJHG 23, 957-62. PMID: 25315659

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human SASH1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SASH1 Polyclonal Antibody (HF745014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SASH1 Polyclonal Antibody (HF745014)

概述

图片

参考文献

产品说明书

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