Anti-Human TRIM37 Polyclonal Antibody (HF616014)

价格:

规格：

50ug
100ug

数量：

联系我们

一键复制产品信息

概述
图片
参考文献
产品说明书

概述

货号

HF616014

品牌

abinScience

描述

Anti-Human TRIM37 Polyclonal Antibody (HF616014) is a rabbit polyclonal antibody detecting TRIM37 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human TRIM37 (Ser275-Ser405).

靶标

E3 ubiquitin-protein ligase TRIM37, 2.3.2.27, Mulibrey nanism protein, RING-type E3 ubiquitin transferase TRIM37, Tripartite motif-containing protein 37, TRIM37, KIAA0898, MUL, POB1

纯化方式

Purified by antigen affinity column.

Accession号

O94972

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

E3 ubiquitin-protein ligase TRIM37 is a ~107 kDa protein. E3 ubiquitin-protein ligase required to prevent centriole reduplication. Probably acts by ubiquitinating positive regulators of centriole reduplication. Mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression: associates with some Polycomb group (PcG) multiprotein PRC2-like complex and mediates repression of target genes. Also acts as a positive regulator of peroxisome import by mediating monoubiquitination of PEX5 at 'Lys-472': monoubiquitination promotes PEX5 stabilitation by preventing its polyubiquitination and degradation by the proteasome. Has anti-HIV activity.

1. Kallijärvi, J. et al. (2005) Experimental cell research 308, 146-55. PMID: 15885686

2. Balestra, FR. et al. (2013) Developmental cell 25, 555-71. PMID: 23769972

3. Bhatnagar, S. et al. (2014) Nature 516, 116-20. PMID: 25470042

4. Wang, W. et al. (2017) The Journal of cell biology 216, 2843-2858. PMID: 28724525

5. Tabah, AA. et al. (2014) The Journal of general virology 95, 960-967. PMID: 24317724

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human TRIM37 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TRIM37 Polyclonal Antibody (HF616014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TRIM37 Polyclonal Antibody (HF616014)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价