

| 货号 | HF883014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human SOX30 Polyclonal Antibody (HF883014) is a rabbit polyclonal antibody detecting SOX30 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human SOX30 (Thr292-Gly403). | ||||||||
| 靶标 | Transcription factor SOX-30, SOX30 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | O94993 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Transcription factor SOX-30 (SOX30) is a ~81 kDa protein. Acts both as a transcriptional activator and a repressor. Binds to the DNA sequence 5'-ACAAT-3' and shows a preference for guanine residues surrounding this core motif. Binds to its own promoter and activates its own transcription. Required to activate the expression of postmeiotic genes involved in spermiogenesis. Binds to the promoter region of CTNNB1 and represses its transcription which leads to inhibition of Wnt signaling. 1. Osaki, E. et al. (1999) Nucleic acids research 27, 2503-10. PMID: 10359848 2. Han, F. et al. (2018) EBioMedicine 31, 253-266. PMID: 29739711 | ||||||||
| Note | For research use only. |

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