Anti-Human ESRRB Polyclonal Antibody (HF928014)

价格:

规格：

50ug
100ug

数量：

联系我们

一键复制产品信息

概述
图片
参考文献
产品说明书

概述

货号

HF928014

品牌

abinScience

描述

Anti-Human ESRRB Polyclonal Antibody (HF928014) is a rabbit polyclonal antibody detecting ESRRB in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human ESRRB (Gly235-Val433).

靶标

ERR-beta, NR3B2, Estrogen-related receptor beta, ESRL2, Estrogen receptor-like 2, ERR beta-2, ESRRB, Nuclear receptor subfamily 3 group B member 2, Steroid hormone receptor ERR2, ERRB2

纯化方式

Purified by antigen affinity column.

Accession号

O95718

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Steroid hormone receptor ERR2 (ESRRB) is a ~48 kDa protein. Transcription factor that binds a canonical ESRRB recognition (ERRE) sequence 5'TCAAGGTCA-3' localized on promoter and enhancer of targets genes regulating their expression or their transcription activity. Plays a role, in a LIF-independent manner, in maintainance of self-renewal and pluripotency of embryonic and trophoblast stem cells through different signaling pathways including FGF signaling pathway and Wnt signaling pathways. Involved in morula development (2-16 cells embryos) by acting as a regulator at the 8-cell stage. Upon FGF signaling pathway activation, interacts with KDM1A by directly binding to enhancer site of ELF5 and EOMES and activating their transcription leading to self-renewal of trophoblast stem cells. Also regulates expression of multiple rod-specific genes and is required for survival of this cell type.

1. Zhou, W. et al. (2007) Molecular and cellular endocrinology 278, 52-62. PMID: 17920186

2. Bombail, V. et al. (2010) Molecular and cellular endocrinology 314, 53-61. PMID: 19755138

3. Cho, Y. et al. (2013) The Journal of biological chemistry 288, 25207-25218. PMID: 23836911

Note

For research use only.

图片

Western blot

Western blot analysis was performed using anti-ESRRB polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse heart lysate
Lane 2: Rat heart lysate

参考文献

产品说明书

Anti-Human ESRRB Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ESRRB Polyclonal Antibody (HF928014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ESRRB Polyclonal Antibody (HF928014)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价