

| 货号 | HY326014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human UROD Polyclonal Antibody (HY326014) is a rabbit polyclonal antibody detecting UROD in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human UROD (Met1-Asn367). | ||||||||
| 靶标 | Uroporphyrinogen decarboxylase, UPD, URO-D, 4.1.1.37, UROD | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P06132 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Uroporphyrinogen decarboxylase (UROD) is a ~40 kDa protein. Catalyzes the sequential decarboxylation of the four acetate side chains of uroporphyrinogen to form coproporphyrinogen and participates in the fifth step in the heme biosynthetic pathway. Isomer I or isomer III of uroporphyrinogen may serve as substrate, but only coproporphyrinogen III can ultimately be converted to heme. In vitro also decarboxylates pentacarboxylate porphyrinogen I. 1. Brady, JJ. et al. (2000) The Journal of investigative dermatology 115, 868-74. PMID: 11069625 2. Phillips, JD. et al. (2001) Blood 98, 3179-85. PMID: 11719352 3. Phillips, JD. et al. (2003) The EMBO journal 22, 6225-33. PMID: 14633982 4. Cunha, L. et al. (2008) Proteins 71, 855-73. PMID: 18004775 5. To-Figueras, J. et al. (2011) The British journal of dermatology 165, 499-505. PMID: 21668429 6. Ged, C. et al. (2002) Archives of dermatology 138, 957-60. PMID: 12071824 | ||||||||
| Note | For research use only. |

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