Anti-Human FBXO45 Polyclonal Antibody (HY575014)

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概述
图片
参考文献
产品说明书

概述

货号

HY575014

品牌

abinScience

描述

Anti-Human FBXO45 Polyclonal Antibody (HY575014) is a rabbit polyclonal antibody detecting FBXO45 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human FBXO45 (Ser41-Gly286).

靶标

F-box/SPRY domain-containing protein 1, F-box only protein 45, hFbxo45, FBXO45, FBX45

纯化方式

Purified by antigen affinity column.

Accession号

P0C2W1

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

F-box/SPRY domain-containing protein 1 (FBXO45) is a ~30 kDa protein. Component of E3 ubiquitin ligase complex consisting of FBXO45, MYCBP2 and SKP1. Functions in substrate recognition but also plays an important role in assembly of the complex. Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration. Regulates neuron migration during brain development through interaction with N-cadherin/CDH2 after secretion via a non-classical mechanism. Plays a role in the regulation of neurotransmission at mature neurons.

1. Desbois, M. et al. (2018) The Journal of biological chemistry 293, 13897-13909. PMID: 29997255

2. Richter, KT. et al. (2020) Cell death and differentiation 27, 758-772. PMID: 31285543

3. Tsai, M. et al. (2022) The Journal of biological chemistry 298, 102698. PMID: 36379255

Note

For research use only.

图片

Western blot

Western blot analysis was performed using anti-FBXO45 polyclonal antibody at FBXO45 on various samples.
Lane 1: Mouse brain lysate

参考文献

产品说明书

Anti-Human FBXO45 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human FBXO45 Polyclonal Antibody (HY575014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human FBXO45 Polyclonal Antibody (HY575014)

概述

图片

参考文献

产品说明书

相关产品推荐

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