Anti-Human H2AB1 Polyclonal Antibody (HY202014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HY202014

品牌

abinScience

描述

Anti-Human H2AB1 Polyclonal Antibody (HY202014) is a rabbit polyclonal antibody detecting H2AB1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human H2AB1 (Met1-Asp115).

靶标

Histone H2A-Bbd type 1, H2A Barr body-deficient, H2A.B, H2A.Bbd, H2AB1, H2AFB1

纯化方式

Purified by antigen affinity column.

Accession号

P0C5Y9

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Histone H2A-Bbd type 1 (H2AB1) is a ~12 kDa protein. Atypical histone H2A which can replace conventional H2A in some nucleosomes and is associated with active transcription and mRNA processing. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Nucleosomes containing this histone are less rigid and organize less DNA than canonical nucleosomes in vivo. They are enriched in actively transcribed genes and associate with the elongating form of RNA polymerase.

1. Tolstorukov, MY. et al. (2012) Molecular cell 47, 596-607. PMID: 22795134

2. Bao, Y. et al. (2004) The EMBO journal 23, 3314-24. PMID: 15257289

3. Okuwaki, M. et al. (2005) Molecular and cellular biology 25, 10639-51. PMID: 16287874

4. Doyen, CM. et al. (2006) The EMBO journal 25, 4234-44. PMID: 16957777

5. Menoni, H. et al. (2007) Molecular and cellular biology 27, 5949-56. PMID: 17591702

6. Eirín-López, JM. et al. (2008) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 22, 316-26. PMID: 17726088

7. González-Romero, R. et al. (2008) Gene 413, 1-7. PMID: 18329190

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human H2AB1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human H2AB1 Polyclonal Antibody (HY202014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human H2AB1 Polyclonal Antibody (HY202014)

概述

图片

参考文献

产品说明书

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