Anti-Human JMJD7 Polyclonal Antibody (HY049014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HY049014

品牌

abinScience

描述

Anti-Human JMJD7 Polyclonal Antibody (HY049014) is a rabbit polyclonal antibody detecting JMJD7 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human JMJD7 (Met1-Asp316).

靶标

Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7, 1.14.11.63, 3.4.-.-, JmjC domain-containing protein 7, Jumonji domain-containing protein 7, L-lysine (3S)-hydroxylase JMJD7, JMJD7

纯化方式

Purified by antigen affinity column.

Accession号

P0C870

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 is a ~35 kDa protein. Bifunctional enzyme that acts both as an endopeptidase and 2-oxoglutarate-dependent monooxygenase. Endopeptidase that cleaves histones N-terminal tails at the carboxyl side of methylated arginine or lysine residues, to generate 'tailless nucleosomes', which may trigger transcription elongation. Preferentially recognizes and cleaves monomethylated and dimethylated arginine residues of histones H2, H3 and H4. After initial cleavage, continues to digest histones tails via its aminopeptidase activity. Additionally, may play a role in protein biosynthesis by modifying the translation machinery.

1. Liu, H. et al. (2017) Proceedings of the National Academy of Sciences of the United States of America 114, E7717-E7726. PMID: 28847961

2. Markolovic, S. et al. (2018) Nature chemical biology 14, 688-695. PMID: 29915238

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human JMJD7 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human JMJD7 Polyclonal Antibody (HY049014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human JMJD7 Polyclonal Antibody (HY049014)

概述

图片

参考文献

产品说明书

相关产品推荐

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