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Anti-Human ZBTB48 Polyclonal Antibody (HY492014)

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  • 50ug
  • 100ug
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概述
货号HY492014
品牌abinScience
描述
Anti-Human ZBTB48 Polyclonal Antibody (HY492014) is a rabbit polyclonal antibody detecting ZBTB48 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
种属反应性Human, Mouse
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human ZBTB48 (Val289-Leu628).
靶标Telomere zinc finger-associated protein, TZAP, Krueppel-related zinc finger protein 3, hKR3, Zinc finger and BTB domain-containing protein 48, Zinc finger protein 855, ZBTB48, HKR3, TZAP, ZNF855
纯化方式Purified by antigen affinity column.
Accession号P10074
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Zinc finger and BTB domain-containing protein 48 (ZBTB48) is a ~77 kDa protein. Plays a critical role in transcriptional regulation and chromatin remodeling. Acts as a regulator of telomere length. Directly binds the telomeric double-stranded 5'-TTAGGG-3' repeat. Preferentially binds to telomeres that have a low concentration of shelterin complex and acts as a regulator of telomere length by initiating telomere trimming, a process that prevents the accumulation of aberrantly long telomeres. Also acts as a transcription regulator that binds to promoter regions.

1. Li, JS. et al. (2017) Science (New York, N.Y.) 355, 638-641. PMID: 28082411
2. Jahn, A. et al. (2017) EMBO reports 18, 929-946. PMID: 28500257
3. Yoon, JH. et al. (2014) The Journal of biological chemistry 289, 4018-31. PMID: 24382891
4. Sugawara, M. et al. (1994) Molecular and cellular biology 14, 8438-50. PMID: 7969177
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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