

| 货号 | HB878014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human ITGB7 Polyclonal Antibody (HB878014) is a rabbit polyclonal antibody detecting ITGB7 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human ITGB7 (Tyr150-Thr392). | ||||||||
| 靶标 | Integrin beta-7, Gut homing receptor beta subunit, ITGB7 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P26010 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Integrin beta-7 (ITGB7) is a ~86 kDa protein. Integrin ITGA4/ITGB7 (alpha-4/beta-7) (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT) (Probable). Integrin ITGA4/ITGB7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract. Also interacts with VCAM1 and fibronectin, an extracellular matrix component (Probable). It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin (Probable). Interactions involve the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin (Probable). 1. Higgins, JM. et al. (2000) The Journal of biological chemistry 275, 25652-64. PMID: 10837471 2. Chen, J. et al. (2003) Nature structural biology 10, 995-1001. PMID: 14608374 | ||||||||
| Note | For research use only. |

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