

| 货号 | HX014014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human SLC12A2 Polyclonal Antibody (HX014014) is a rabbit polyclonal antibody detecting SLC12A2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human SLC12A2 (Asn1002-Ser1212). | ||||||||
| 靶标 | Solute carrier family 12 member 2, Basolateral Na-K-Cl symporter, Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2, SLC12A2, NKCC1 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P55011 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Solute carrier family 12 member 2 (SLC12A2/NKCC1) is a ~131 kDa protein. Cation-chloride cotransporter which mediates the electroneutral transport of chloride, potassium and/or sodium ions across the membrane. Plays a vital role in the regulation of ionic balance and cell volume. 1. Vitari, AC. et al. (2006) The Biochemical journal 397, 223-31. PMID: 16669787 2. Yang, X. et al. (2020) Nature communications 11, 1016. PMID: 32081947 3. Mutai, H. et al. (2020) PLoS genetics 16, e1008643. PMID: 32294086 4. Zhang, S. et al. (2021) Communications biology 4, 226. PMID: 33597714 5. Zhao, Y. et al. (2022) Nature communications 13, 2747. PMID: 35585053 6. Neumann, C. et al. (2022) The EMBO journal 41, e110169. PMID: 36239040 7. Moseng, MA. et al. (2022) Science advances 8, eabq0952. PMID: 36306358 8. Payne, JA. et al. (1995) The Journal of biological chemistry 270, 17977-85. PMID: 7629105 | ||||||||
| Note | For research use only. |

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