Anti-Human TARBP2 Polyclonal Antibody (HS711014)

价格:

规格：

50ug
100ug

数量：

联系我们

一键复制产品信息

概述
图片
参考文献
产品说明书

概述

货号

HS711014

品牌

abinScience

描述

Anti-Human TARBP2 Polyclonal Antibody (HS711014) is a rabbit polyclonal antibody detecting TARBP2 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human TARBP2 (Thr264-Lys366).

靶标

RISC-loading complex subunit TARBP2, TAR RNA-binding protein 2, Trans-activation-responsive RNA-binding protein, TARBP2, TRBP

纯化方式

Purified by antigen affinity column.

Accession号

Q15633

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

RISC-loading complex subunit TARBP2 is a ~39 kDa protein. Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1.

1. Chendrimada, TP. et al. (2005) Nature 436, 740-4. PMID: 15973356

2. Haase, AD. et al. (2005) EMBO reports 6, 961-7. PMID: 16142218

3. Gregory, RI. et al. (2005) Cell 123, 631-40. PMID: 16271387

4. Maniataki, E. et al. (2005) Genes & development 19, 2979-90. PMID: 16357216

5. Lee, Y. et al. (2006) The EMBO journal 25, 522-32. PMID: 16424907

6. Kok, KH. et al. (2007) The Journal of biological chemistry 282, 17649-57. PMID: 17452327

7. MacRae, IJ. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 512-7. PMID: 18178619

8. Fukunaga, R. et al. (2012) Cell 151, 533-46. PMID: 23063653

9. Ling, T. et al. (2019) Molecular immunology 109, 116-125. PMID: 30927622

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human TARBP2 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TARBP2 Polyclonal Antibody (HS711014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TARBP2 Polyclonal Antibody (HS711014)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价