

| 货号 | HA342014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human SUPV3L1 Polyclonal Antibody (HA342014) is a rabbit polyclonal antibody detecting SUPV3L1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human SUPV3L1 (Thr47-Glu722). | ||||||||
| 靶标 | ATP-dependent RNA helicase SUPV3L1, mitochondrial, 3.6.4.13, Suppressor of var1 3-like protein 1, SUV3-like protein 1, SUPV3L1, SUV3 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q8IYB8 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | ATP-dependent RNA helicase SUPV3L1, mitochondrial is a ~87 kDa protein. Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. Involved in the degradation of non-coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. 1. Pietras, Z. et al. (2018) Nature communications 9, 2558. PMID: 29967381 | ||||||||
| Note | For research use only. |

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