

| 货号 | HA292014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human PYCR2 Polyclonal Antibody (HA292014) is a rabbit polyclonal antibody detecting PYCR2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human PYCR2 (Met1-Lys276). | ||||||||
| 靶标 | Pyrroline-5-carboxylate reductase 2, P5C reductase 2, P5CR 2, 1.5.1.2, PYCR2 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q96C36 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Pyrroline-5-carboxylate reductase 2 (PYCR2) is a ~33 kDa protein. Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate to L-proline using NAD(P)H. At physiologic concentrations, has higher specific activity in the presence of NADH. Involved in cellular response to oxidative stress. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). 1. De Ingeniis, J. et al. (2012) PloS one 7, e45190. PMID: 23024808 2. Merrill, MJ. et al. (1989) The Journal of biological chemistry 264, 9352-8. PMID: 2722838 3. Yeh, GC. et al. (1981) The Journal of clinical investigation 67, 1042-6. PMID: 6894153 4. Nakayama, T. et al. (2015) American journal of human genetics 96, 709-19. PMID: 25865492 | ||||||||
| Note | For research use only. |

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