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Anti-Human PYCR2 Polyclonal Antibody (HA292014)

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概述
货号HA292014
品牌abinScience
描述
Anti-Human PYCR2 Polyclonal Antibody (HA292014) is a rabbit polyclonal antibody detecting PYCR2 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human PYCR2 (Met1-Lys276).
靶标Pyrroline-5-carboxylate reductase 2, P5C reductase 2, P5CR 2, 1.5.1.2, PYCR2
纯化方式Purified by antigen affinity column.
Accession号Q96C36
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Pyrroline-5-carboxylate reductase 2 (PYCR2) is a ~33 kDa protein. Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate to L-proline using NAD(P)H. At physiologic concentrations, has higher specific activity in the presence of NADH. Involved in cellular response to oxidative stress. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+).

1. De Ingeniis, J. et al. (2012) PloS one 7, e45190. PMID: 23024808
2. Merrill, MJ. et al. (1989) The Journal of biological chemistry 264, 9352-8. PMID: 2722838
3. Yeh, GC. et al. (1981) The Journal of clinical investigation 67, 1042-6. PMID: 6894153
4. Nakayama, T. et al. (2015) American journal of human genetics 96, 709-19. PMID: 25865492
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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