

| 货号 | HA382014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human MARK4 Polyclonal Antibody (HA382014) is a rabbit polyclonal antibody detecting MARK4 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human MARK4 (Gly57-Lys370). | ||||||||
| 靶标 | MAP/microtubule affinity-regulating kinase 4, 2.7.11.1, MAP/microtubule affinity-regulating kinase-like 1, MARK4, KIAA1860, MARKL1 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q96L34 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | MAP/microtubule affinity-regulating kinase 4 (MARK4) is a ~82 kDa protein. Serine/threonine-protein kinase. Phosphorylates the microtubule-associated protein MAPT/TAU. Also phosphorylates the microtubule-associated proteins MAP2 and MAP4. Involved in regulation of the microtubule network, causing reorganization of microtubules into bundles. Required for the initiation of axoneme extension during cilium assembly. 1. Trinczek, B. et al. (2004) The Journal of biological chemistry 279, 5915-23. PMID: 14594945 2. Schneider, A. et al. (2004) Journal of neurochemistry 88, 1114-26. PMID: 15009667 3. Li, L. et al. (2013) The Journal of biological chemistry 288, 703-8. PMID: 23184942 4. Gu, GJ. et al. (2013) Neuromolecular medicine 15, 458-69. PMID: 23666762 5. Rovina, D. et al. (2014) European journal of cell biology 93, 355-65. PMID: 25123532 6. Kuhns, S. et al. (2013) The Journal of cell biology 200, 505-22. PMID: 23400999 7. Li, X. et al. (2017) Nature communications 8, 15986. PMID: 28656979 | ||||||||
| Note | For research use only. |

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