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Anti-Human MARK4 Polyclonal Antibody (HA382014)

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概述
货号HA382014
品牌abinScience
描述
Anti-Human MARK4 Polyclonal Antibody (HA382014) is a rabbit polyclonal antibody detecting MARK4 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
种属反应性Human, Mouse
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human MARK4 (Gly57-Lys370).
靶标MAP/microtubule affinity-regulating kinase 4, 2.7.11.1, MAP/microtubule affinity-regulating kinase-like 1, MARK4, KIAA1860, MARKL1
纯化方式Purified by antigen affinity column.
Accession号Q96L34
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

MAP/microtubule affinity-regulating kinase 4 (MARK4) is a ~82 kDa protein. Serine/threonine-protein kinase. Phosphorylates the microtubule-associated protein MAPT/TAU. Also phosphorylates the microtubule-associated proteins MAP2 and MAP4. Involved in regulation of the microtubule network, causing reorganization of microtubules into bundles. Required for the initiation of axoneme extension during cilium assembly.

1. Trinczek, B. et al. (2004) The Journal of biological chemistry 279, 5915-23. PMID: 14594945
2. Schneider, A. et al. (2004) Journal of neurochemistry 88, 1114-26. PMID: 15009667
3. Li, L. et al. (2013) The Journal of biological chemistry 288, 703-8. PMID: 23184942
4. Gu, GJ. et al. (2013) Neuromolecular medicine 15, 458-69. PMID: 23666762
5. Rovina, D. et al. (2014) European journal of cell biology 93, 355-65. PMID: 25123532
6. Kuhns, S. et al. (2013) The Journal of cell biology 200, 505-22. PMID: 23400999
7. Li, X. et al. (2017) Nature communications 8, 15986. PMID: 28656979
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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