Anti-Human HDGFL2 Polyclonal Antibody (HA200014)

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100ug

数量：

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概述
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参考文献
产品说明书

概述

货号

HA200014

品牌

abinScience

描述

Anti-Human HDGFL2 Polyclonal Antibody (HA200014) is a rabbit polyclonal antibody detecting HDGFL2 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human HDGFL2 (Met1-Asn87).

靶标

Hepatoma-derived growth factor-related protein 2, HDGF-related protein 2, HRP-2, Hepatoma-derived growth factor 2, HDGF-2, HDGFL2, HDGF2, HDGFRP2, HRP2, UNQ785/PRO1604

纯化方式

Purified by antigen affinity column.

Accession号

Q7Z4V5

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Hepatoma-derived growth factor-related protein 2 (HDGFL2) is a ~74 kDa protein. Acts as an epigenetic regulator of myogenesis in cooperation with DPF3a (isoform 2 of DPF3/BAF45C). Associates with the BAF complex via its interaction with DPF3a and HDGFL2-DPF3a activate myogenic genes by increasing chromatin accessibility through recruitment of SMARCA4/BRG1/BAF190A (ATPase subunit of the BAF complex) to myogenic gene promoters. Promotes the repair of DNA double-strand breaks (DSBs) through the homologous recombination pathway by facilitating the recruitment of the DNA endonuclease RBBP8 to the DSBs. Preferentially binds to chromatin regions marked by H3K9me3, H3K27me3 and H3K36me2. Involved in cellular growth control, through the regulation of cyclin D1 expression.

1. Zhu, X. et al. (2020) Nucleic acids research 48, 6563-6582. PMID: 32459350

2. Baude, A. et al. (2016) Nucleic acids research 44, 2214-26. PMID: 26721387

3. Gao, K. et al. (2015) Biochemical and biophysical research communications 458, 849-55. PMID: 25689719

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human HDGFL2 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human HDGFL2 Polyclonal Antibody (HA200014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human HDGFL2 Polyclonal Antibody (HA200014)

概述

图片

参考文献

产品说明书

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