

| 货号 | HA280014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human MXRA8 Polyclonal Antibody (HA280014) is a rabbit polyclonal antibody detecting MXRA8 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human MXRA8 (His23-Glu293). | ||||||||
| 靶标 | Matrix remodeling-associated protein 8, Limitrin, MXRA8 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q9BRK3 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Matrix remodeling-associated protein 8 (MXRA8) is a ~49 kDa protein. Transmembrane protein which can modulate activity of various signaling pathways, probably via binding to integrin ITGAV:ITGB3. Mediates heterophilic cell-cell interactions in vitro. Inhibits osteoclastogenesis downstream of TNFSF11/RANKL and CSF1, where it may function by attenuating signaling via integrin ITGB3 and MAP kinase p38. Plays a role in cartilage formation where it promotes proliferation and maturation of growth plate chondrocytes. Stimulates formation of primary cilia in chondrocytes. 1. Jung, YK. et al. (2012) Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 27, 2024-34. PMID: 22492581 2. Han, SW. et al. (2013) Cardiovascular research 98, 73-82. PMID: 23386276 | ||||||||
| Note | For research use only. |

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