

| 货号 | HA043014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human RCCD1 Polyclonal Antibody (HA043014) is a rabbit polyclonal antibody detecting RCCD1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human RCCD1 (Met1-Ser376). | ||||||||
| 靶标 | RCC1 domain-containing protein 1, RCCD1 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | A6NED2 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | RCC1 domain-containing protein 1 (RCCD1) is a ~40 kDa protein. Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8. Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation. Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8. 1. Marcon, E. et al. (2014) Cell reports 8, 297-310. PMID: 24981860 2. Wu, J. et al. (2017) Cancer letters 400, 18-29. PMID: 28455245 | ||||||||
| Note | For research use only. |

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