

| 货号 | HA176014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human SLC9A9 Polyclonal Antibody (HA176014) is a rabbit polyclonal antibody detecting SLC9A9 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human SLC9A9. | ||||||||
| 靶标 | Sodium/hydrogen exchanger 9, Na(+)/H(+) exchanger 9, NHE-9, Solute carrier family 9 member 9, SLC9A9, NHE9, Nbla00118 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q8IVB4 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Sodium/hydrogen exchanger 9 (SLC9A9) is a ~72 kDa protein. Endosomal Na(+), K(+)/H(+) antiporter. Mediates the electroneutral exchange of endosomal luminal H(+) for a cytosolic Na(+) or K(+) (Probable). By facilitating proton efflux, SLC9A9 counteracts the acidity generated by vacuolar (V)-ATPase, thereby limiting luminal acidification. Regulates organellar pH and consequently, e.g., endosome maturation and endocytic trafficking of plasma membrane receptors and neurotransporters. Promotes the recycling of transferrin receptors back to the cell surface to facilitate additional iron uptake in the brain. 1. Nakamura, N. et al. (2005) The Journal of biological chemistry 280, 1561-72. PMID: 15522866 2. Kondapalli, KC. et al. (2013) Nature communications 4, 2510. PMID: 24065030 3. Beydoun, R. et al. (2017) The Journal of biological chemistry 292, 4293-4301. PMID: 28130443 | ||||||||
| Note | For research use only. |

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